Serum manufacturing · Hauppauge, New York
Serum Manufacturing for Skin Care Brands
Private label serums from a catalog of more than 300 formulas, or full custom serum contract manufacturing from a blank page. Made in one NSF GMP, FDA-registered New York facility, with the botanical extracts produced on the same site.
- Published minimum order quantity: 5,000 units, in 1 oz and 2 oz bottles
- We make our own botanical extracts — sourced globally, made in New York, not a third-party purchase
- Water-thin gel, light emulsified, oil-phase and biphasic serums
- NSF GMP · FSSC 22000 · FDA-registered facility · USDA Organic · Kosher · Halal
Get a quote on your serum
Tell us the serum you have in mind. A formulator reviews every request — not a call center.
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NSF GMP
FSSC 22000
FDA-registered facility
USDA Organic
Kosher
Halal
Botanicals sourced globally
Extracts made in New York since 1972
1972
Extracting botanicals since
160,000 sq ft
FDA-registered New York facility
5,000 units
Minimum order quantity, 1 oz and 2 oz bottles
300+
Private label formulas ready now
What kinds of serums can you manufacture?
BioB Manufacturing makes water-thin gel serums, light emulsified serums, oil-phase and biphasic serums, and botanical-extract-forward serums, filled into glass dropper bottles, airless pumps and treatment bottles. The formula can come from our catalog of more than 300 private label bases, from a modified base, or from ground-up custom development.
Water-thin gel serums
A single water phase thickened with a gum or synthetic gelling polymer. No oil phase, no emulsifier — the clearest serums, and the format best suited to a glass dropper.
Light emulsified serums
A small oil phase carried in water with an emulsifier, giving a milky or translucent fluid. The route when a formula must carry oil-soluble material and still feel weightless.
Oil-phase and biphasic serums
Anhydrous facial oils, and two-phase serums that separate in the bottle and are shaken before use. Biphasic fills need a pack that shows the split cleanly and holds the ratio.
Botanical-extract-forward serums
Serums built around botanical extracts rather than one synthetic ingredient. We make the extracts ourselves, so the specified material and the material in the tank share one origin.
Why serum is a smart business play for skin care brands
Serum is the highest-margin, fastest-growing format in facial skin care, and the one buyers use to judge whether a brand is serious. It is also the easiest format to add to an existing line without reworking the rest of it.
Market share you can take
Serums lead growth in facial care because customers treat them as the step where results happen. A brand without one is leaving the most-searched product in the category to a competitor.
Premium price, small fill
A 1 oz or 2 oz serum carries a premium price on a small fill. The extract inside the bottle is most of what the customer pays for, which is exactly where making our own botanical extracts matters.
The natural line extension
A serum sits beside a cream, a cleanser or a supplement without cannibalizing any of them. It is the product that turns a single hero SKU into a regimen.
Proven bases, your brand
Start from a serum already in the market through other brands, modify it, or develop one to your benchmark. Three routes, one facility, one documentation package.
Which botanical ingredients can a serum carry, and at what level?
That is a formulation conversation, not a catalog answer. Whether an ingredient works in a serum, at what percentage and at what pH, depends on the system it goes into: the solvent, what competes for the same solubility, and how the pack behaves. We will tell you what looks workable in your system and what we would want to test first. What we will not do is promise to hold any named ingredient at any named level, because that answer differs in every formula.
What is the minimum order quantity for serum manufacturing?
The minimum order quantity for a serum is 5,000 units. We fill serums in 1 oz and 2 oz bottles, the sizes premium serums sell in, and the number is published, not held back for a call.
| Serum format and pack | Fill | Minimum order quantity | Lead time |
|---|---|---|---|
| Gel, emulsified, oil-phase or biphasic serum, glass dropper or airless pump | 1 oz | 5,000 units | About 12 weeks |
| Gel, emulsified, oil-phase or biphasic serum, glass dropper or airless pump | 2 oz | 5,000 units | About 12 weeks |
Components are confirmed at quote. Lead time is about 12 weeks from approved formula and packaging to finished goods; packaging component availability, not filling capacity, is the usual variable.
Bulk serum and other delivery systems
Not every program ends in a retail bottle. We also supply serum in bulk to partners who fill it themselves, who manufacture samples and sachets for sampling programs, or who need the same formula in a different delivery system.
- Bulk serum shipped in drums or pails to your filler or sample manufacturer
- The same formula filled into sachets, ampoules or trial sizes through a sampling partner
- Serum concentrates for brands that finish the product elsewhere
Tell us the delivery system at scoping and we will quote the bulk format alongside the finished bottle.
Private label, semi-custom or full custom serum?
Three routes. Private label puts your brand on one of more than 300 existing formulas. Semi-custom starts from one of those bases and changes the botanical ingredients, the viscosity or the scent. Full custom develops a serum from a blank page. Semi-custom is the most common start, because a proven base removes most of the formulation risk.
Private label serum
You choose from the catalog and we fill it under your brand. Fastest route, lowest development effort, formula already made and documented. Best when the differentiation lives in the brand, not the chemistry.
Semi-custom serum
We start from a proven base and change what matters — swap or add a botanical extract, change the botanical ingredients, adjust viscosity and slip, change or drop the fragrance. Yours, without a ground-up development cycle.
Full custom serum
Ground-up contract manufacturing with our formulators, developed to a benchmark or specification you provide, or a texture you want to hit. The longest route, the most sampling, and the only one nobody else can buy.
Where do the botanical extracts in your serums come from?
We make them. Bio-Botanica has extracted botanicals since 1972, and BioB Manufacturing is the finished-goods arm of that business. Our botanical extracts are sourced globally and made in New York. When a serum in our catalog calls for a botanical extract, that extract is produced in the same Hauppauge facility that fills the bottle.
That matters more in a serum than in almost any other format. A serum is a thin, often clear system where the extract is much of what the buyer is paying for, and any change to it shows immediately in color, odor and clarity. Buying on the open market means a change of supplier is a change of material — and in a clear serum, that is something your customer can see. Topical serums use glycerin-based botanical extracts, not the alcohol-free extracts used on the ingestible side.
See our standards and certifications for how that supply is qualified and documented.
We do not white label. Every lot is made fresh to order.
White label means pre-made stock on a shelf waiting for a label. We do not keep one. Your product is manufactured when you order it, so it ships with its full shelf life, every repeat run is made to the same specification, and nothing you sell has been sitting in someone else's warehouse. It is one of the reasons retailers and marketplaces accept our documentation without a second look.
What happens from first call to shipped lot
Six steps, about 12 weeks from approved formula and packaging to finished goods. The order never changes; what moves the date is how much of the specification already exists when you arrive and how quickly packaging components can be secured.
1
Scope call
Product, format, volume and timing. We tell you plainly whether our minimum order quantities fit your plan and whether private label or custom is the right route.
2
Formula
Choose a formulation from our proven private label catalog, or we review the specification you bring and develop one to your benchmark.
3
Preliminary quote
Pricing, minimum order quantities, components and lead time, so you know the numbers before anyone makes a sample.
4
Samples and specification sign-off
You assess samples until you approve. The finished-product specification and the test panel are fixed in writing here. Nothing scales until the sample is the product you want to sell.
5
Label and artwork review
You supply the artwork. We supply the ingredient and specification data it has to reflect, and check the printed panel against the actual product before the run.
6
Production, QC release and documentation
Manufacture under NSF GMP, release against the agreed specification, and ship from New York with the Certificate of Analysis and documentation package for the lot. Repeat runs start at step five unless the specification has changed.
What testing and documentation comes with a serum batch?
Each batch is manufactured against a batch record in an NSF GMP, FDA-registered facility and released against the finished-goods specification agreed with you before production. You receive a Certificate of Analysis for the batch, the ingredient declaration in INCI order, and the manufacturing documentation set out in your quality agreement.
- A Certificate of Analysis for the batch, against the agreed specification — not a generic template.
- The finished-goods specification itself: appearance, pH, viscosity and the other attributes the formula is released on.
- The ingredient declaration in INCI order, in the form your labeling and your FDA listing need.
- Batch and lot traceability back through the manufacturing record.
- Confirmation of the facility's NSF GMP certification and its FDA facility registration.
- Retention samples and their retention period, where set out in the quality agreement.
Which tests run, and who runs them, is decided at scoping and written into the specification rather than left implied. Microbial testing, challenge testing of the preservative system, stability and compatibility work in the actual pack, and any testing needed to support a claim are scoped per formula. The quote says which sit inside the program, which are quoted separately, and which go to a third-party lab.
Who is responsible for MoCRA compliance on a serum?
Responsibility is split. Under the Modernization of Cosmetics Regulation Act the manufacturer registers and biennially renews the facility with FDA. The brand is normally the Responsible Person: the party that lists the product with FDA, whose name appears on the label, and that holds the safety substantiation records for the finished serum.
| MoCRA obligation | Who normally holds it |
|---|---|
| Facility registration and biennial renewal | The manufacturer. BioB registers and maintains the Hauppauge facility. |
| Good manufacturing practice at the site | The manufacturer. |
| Batch records, finished-goods specification and the batch COA | The manufacturer. |
| Cosmetic product listing with FDA | The brand, as Responsible Person. |
| Responsible Person name and contact on the label | The brand, as Responsible Person. |
| Adequate substantiation of safety for the finished product | The brand, as Responsible Person, built from formulation, ingredient and testing information. |
| Serious adverse event reporting and the associated records | The brand, as Responsible Person. |
We supply the manufacturing-side information a Responsible Person needs for that file — formula and ingredient information, the specification, the batch documentation — but the listing, the label and the safety substantiation file are the brand's to hold. FDA sets this out on its page covering registration and listing of cosmetic product facilities and products.
One more thing to raise at scoping. A serum is only a cosmetic if it is sold as one. A serum marketed as a sunscreen, or as an acne treatment, is an over-the-counter drug product in the United States and sits under the OTC monograph system, not under MoCRA. That changes the label, the testing and the whole regulatory pathway, so say so on the first call.
Why brands choose BioB for serum manufacturing
We make the botanical extracts
Botanical extraction in house since 1972, in the same building as the filling line. Sourced globally, made in New York, so traceability starts with us, not a broker.
Made fresh to order
No white label stock. Every lot is manufactured when you order it and ships with its full shelf life.
Minimum order quantities in print
5,000 units in 1 oz or 2 oz bottles, in writing, on this page.
One US site
A single 160,000 sq ft FDA-registered facility in New York. No import step, no tariff variable, no offshore transit between you and a stockout.
Supplements and personal care together
Liquids, capsules, tablets, powders, oral care and pet wellness alongside serums, creams, lotions and sprays. One vendor, one quality system, one documentation package.
We tell you what you own
The MoCRA split above is published here because you should know it before signing a supply agreement, not after your first listing deadline.
Serum manufacturing FAQ
What is the minimum order quantity for serum manufacturing?
5,000 units, filled in 1 oz or 2 oz bottles. Those are the sizes premium serums sell in, and the number is published here rather than held back for a call.
Can you supply serum in bulk?
Yes. We ship bulk serum in drums or pails to fillers and sample manufacturers, and can quote the same formula in sachets, ampoules or trial sizes through a sampling partner. Ask for the bulk format at scoping and it is quoted alongside the finished bottle.
What is the difference between a gel serum and an emulsified serum?
A gel serum is a single water phase thickened with a gelling polymer: clear, light, no oil and no emulsifier. An emulsified serum carries a small oil phase in water with an emulsifier, so it looks milky or translucent and can carry oil-soluble material.
Should I choose a private label serum or a custom serum?
Private label if you need a credible serum in the line quickly and the differentiation is in your brand. Full custom if the formula itself is the product. Semi-custom sits between: start from a proven base, change the botanical ingredients, viscosity or scent, and skip most of a development cycle.
What packaging can you fill serums into, and how is compatibility confirmed?
Glass dropper bottles, airless pumps, and treatment bottles with a pump or fine mist are the common serum packs. Compatibility is confirmed with your actual formula in your actual component rather than assumed from the pack type, because a clear gel in clear glass shows every issue a cream would hide.
Who is the Responsible Person for a serum under MoCRA?
Normally the brand. Under MoCRA the manufacturer registers and biennially renews the facility, while the Responsible Person named on the label lists the product with FDA and maintains the safety substantiation records. For a private label or contract-manufactured serum, that Responsible Person is almost always the brand owner.
Do you provide a Certificate of Analysis and batch documentation?
Yes. Each batch is released against the finished-goods specification agreed before production and ships with a Certificate of Analysis for that batch, the ingredient declaration in INCI order, and lot traceability. Retention samples and their retention period are set out in the quality agreement.
Can I get samples before committing to production?
Yes. Physical samples are part of every route, whether the serum comes from the catalog, a modified base or ground-up development. You assess texture, color, odor, slip and behavior in the intended pack before anything is scheduled. Iteration rounds are normal and are scoped with the project.
What sets the timeline on a serum project?
About 12 weeks from approved formula and packaging to finished goods. The variable is almost always packaging component availability rather than filling capacity: the glass dropper, the pump or the decorated component is what holds a serum up. The other movers are how many sampling rounds you need and how quickly the specification, artwork and quality agreement are signed off.
Where do the botanical extracts in your serums come from?
From our own facility. Bio-Botanica has extracted botanicals in Hauppauge, New York since 1972, and BioB Manufacturing is its finished-goods arm. Our extracts are sourced globally and made in New York. Topical serums use glycerin-based botanical extracts, so the material named in your specification and the material in the tank come from the same site.
What shelf life and period-after-opening should I expect on a serum?
Those are not numbers a manufacturer can hand you off a list. They follow from the formula, the preservative system, the pack and the testing that supports them. We agree a target at scoping, say what testing would be needed to support it, and state on the quote who performs it.
Do you make creams and lotions as well as serums?
Yes. Creams, lotions, sprays and oils run on the same 5,000-unit minimum order quantity, and we make ingestibles in the same facility: liquids, capsules, tablets and powders. A serum with a companion cream or supplement can stay with one manufacturer.
Do you white label serums?
No. Every lot is made fresh to order, so your serum ships with its full shelf life and every repeat run matches the same specification.
Get a quote on your serum program
Tell us the serum you have in mind — a catalog base under your brand, a modified version of one, or something that does not exist yet. A formulator reads it and replies the same business day. Published minimum order quantity: 5,000 units in 1 oz or 2 oz bottles.