Custom supplement manufacturing · Hauppauge, New York
Contract Manufacturing for Supplements, Made to Your Specification
BioB Manufacturing builds supplements to a formula you own, or develops one with you from a brief. We extract our own botanicals, produce in a single FDA-registered US facility, and publish our minimums instead of hiding them behind a request form.
- Published minimums: liquids from 2,500 units, capsules and tablets from 300,000 units
- NSF GMP certified, FDA-registered facility, USDA Organic, Kosher and Halal
- Botanical extracts made in house since 1972, so we control the actives in your formula
Prefer to talk it through? Book a 30-minute call with Emily Slater
Get a manufacturing quote
Tell us what you want to make and we will come back with formats, minimums and a schedule.
Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.
No obligation. We reply the same business day.
NSF GMP certified
FDA-registered facility
USDA Organic
Kosher
Halal
Made in Hauppauge, NY
Extracting botanicals since 1972
20,000+
Kg of botanicals extracted per week
160,000
Sq ft FDA-registered facility, New York
2,500
Unit minimum, liquids 8 oz and larger
300+
Ready formulas if you would rather not develop one
What is contract manufacturing for supplements?
Contract manufacturing for supplements is an arrangement in which a brand owns the product specification and a manufacturer produces it. The manufacturer sources or makes the raw materials, blends, fills, tests and documents every lot under 21 CFR Part 111. The brand owns the formula, the label and the regulatory responsibility attached to it.
How is contract manufacturing different from private label?
Private label starts from a formula the manufacturer already owns. You select it from a catalog, put your brand on it and order it. Contract manufacturing starts from a specification you own or commission: your ingredient list, your actives, your potencies, your release limits. Private label is the faster and lower-cost route to market. Contract manufacturing gives you a product a competitor cannot simply buy off the same shelf.
This page covers the custom route. If you want a proven formula you can brand and ship sooner, that is our private label supplements program, with more than 300 existing formulations already in the catalog.
Where does white label fit?
White label and private label are used interchangeably across the industry, and both describe the same thing: a finished product the manufacturer developed, sold under your brand. Neither gives you exclusivity over the formula. Contract manufacturing does, because the specification originates with you.
Who is contract manufacturing right for?
It suits brands with a formula they already sell and want moved to a better manufacturer, brands whose current product needs reformulating around a supply or cost problem, and brands with a clinical or ingredient position no catalog formula can express. It also suits companies that need an ingestible product and a companion topical from one quality system rather than two vendors.
What supplement formats can BioB manufacture?
BioB manufactures liquid supplements including alcohol-free formats, capsules, tablets, powders, oral care products and pet wellness products. Liquids are the house specialty: Bio-Botanica has produced botanical extracts since 1972, so liquid actives are made in the same building where your finished product is filled.
Liquid supplements and alcohol-free formats
Liquid extracts, tinctures, concentrates, drops and shots, in both traditional and alcohol-free bases. Alcohol-free extraction is a genuine specialism here, not a line item. It matters for brands serving customers who avoid alcohol for religious, age or preference reasons, and for products aimed at children. Most contract manufacturers subcontract liquids or decline them outright.
Browse liquid supplements →Capsules
Two-piece capsules filled with powder blends, botanical extracts and standardized actives. Suitable for multi-ingredient formulas where taste masking would otherwise dictate the format.
Browse capsule supplements →Tablets
Compressed tablets for higher-volume programs and formulas where a smaller unit or a lower cost per serving is the priority.
Powders
Blended powders for tub, sachet or stick-pack presentation, including botanical extract powders produced in house.
Oral care
Botanical oral care products manufactured under the same quality system as the ingestible range.
Browse oral care →Pet wellness
Pet wellness products in liquid and powder presentation, built from the same extract library as the human range.
Browse pet wellness →We also make skin, hair and body care in the same facility. If your launch pairs a supplement with a topical, see private label skin care manufacturing, or browse the full product range and the product directory.
What are the minimum order quantities for contract manufacturing?
Liquid supplements under 8 oz start at 5,000 units. Liquid supplements 8 oz and larger start at 2,500 units. Capsules and tablets start at 300,000 units total. Other formats are confirmed at quote. We publish these because a minimum you only learn about after three calls is a minimum designed to trap you.
| Format | Minimum order quantity | Notes |
|---|---|---|
| Liquid supplements, under 8 oz | 5,000 units | Includes alcohol-free liquid extracts, tinctures, drops and shots |
| Liquid supplements, 8 oz and larger | 2,500 units | The lowest published minimum we offer in any format |
| Capsules | 300,000 units total | Counted across the production run rather than per bottle count |
| Tablets | 300,000 units total | Counted across the production run rather than per bottle count |
| Powders, oral care, pet wellness and other formats | Confirmed at quote | Driven by fill size, packaging format and blend complexity |
How long does contract manufacturing take?
About 12 weeks from approved formula and packaging to finished goods. The variable is almost always packaging component availability rather than manufacturing capacity: bottles, closures, droppers, cartons, labels and any ingredient that has to be qualified before first use. Line time for a supplement run is rarely the constraint. Tell us what the pack looks like and we will confirm that schedule with your quote.
Three ways to run a custom supplement program
Custom is not one thing. Most projects arrive as one of three: a product that already exists and needs changing, an idea that needs a formula built around it, or a formula you own that needs to be produced somewhere better. Each has a different starting point and a different amount of work before first production.
1. Reformulation of a product you already sell
You have a product on the market and something about it has to change: an ingredient has become hard to source, a claim needs different substantiation, a flavor is failing, an alcohol base needs to become alcohol-free, or the cost per unit no longer works. We take the existing specification apart, identify what is driving the problem, and rebuild around it while holding the parts of the product your customers recognize.
2. Custom development from a brief
You have a position, an audience and a target format, but no formula. We start from the brief: which actives, at what levels, in which base, at what taste and stability profile, inside which regulatory framing. Our formulators work with the extract library Bio-Botanica has built since 1972, so the actives conversation is a conversation with the people who make them.
3. Scale-up or transfer of a formula you own
You own the specification and you need it produced at volume, or produced somewhere that will document it properly. We repeat your formula, qualify the raw materials against your specification, run trial and pilot batches, and confirm that what comes off our line matches what you approved. Transfers are where documentation gaps usually surface, and we would rather find them before first production than during it.
If none of these describe you and the honest answer is that a proven formula would get you to market faster, say so on the form. We will point you at private label supplements instead. A custom program you do not need is the most expensive way to launch.
We make the actives, not just the finished product
BioB Manufacturing is the finished-goods arm of Bio-Botanica, which has extracted botanicals since 1972. The extracts in your formula and the finished bottle come out of the same 160,000 square foot facility in Hauppauge, New York. That is unusual. Most contract manufacturers on this search buy their actives from a broker and pass whatever arrives on to you.
- Traceability that does not stop at a supplier COA, because for our own extracts we are the supplier
- Fewer parties between the raw botanical and your finished lot, so fewer places a specification can drift
- Formulation conversations with the people who actually make the extract, not with a purchasing desk
See our standards and certifications for the full list of what the facility holds.
What botanical extract capabilities does BioB have in house?
All run by our parent company, Bio-Botanica, on the same Hauppauge, New York campus: botanical extraction, liquid compounding, spray and vacuum tray drying, custom blends, and quality testing for supplements, foods and beverages, personal care, and cosmetics.
Botanical extraction
Our proprietary Bio-Chelated® process combines cold percolation with low-heat distillation to help preserve the botanical’s naturally occurring constituents.
- Extraction capacity of more than 20,000 kg per week
- Water, alcohol, and aqueous extraction options
- Botanical ingredients tailored to customer specifications
Liquid compounding
We manufacture liquid botanical ingredients and custom blends for a range of formulation needs.
- Batch sizes from 50 to 3,300 gallons
- Equipment capable of handling high-viscosity and high-solids formulations
- Alcohol-free, glycerin-based extract options
- Single-botanical ingredients and custom botanical blends
Spray drying
Our spray drying capabilities transform liquid botanical extracts into powdered ingredients for applications such as beverage mixes and fast-dissolve formulations.
- Production capacity of up to 100 kg per hour
- Custom spray drying to customer specifications
- Maltodextrin carrier options
- In-stock spray-dried ingredients available
Vacuum tray drying
Vacuum tray drying produces powdered botanical extracts suited to capsule and tablet formulations.
- Production output ranging from 150 to 1,500 kg per day
- Dicalcium phosphate carrier options
- Powders with flow and compression properties suited to solid dosage applications
Custom extracts and botanical blends
Work with our team to develop an ingredient around your formulation requirements. Custom projects may include:
- Liquid or powdered botanical extracts
- Multi-botanical blends
- Extracts developed to match existing ingredient specifications
- Hard-to-source botanicals
- Blends that help simplify ingredient purchasing and inventory
Projects are evaluated based on technical feasibility, production requirements, and anticipated volume.
On-site quality control and microbiology
Our on-site quality control center and microbiology laboratory support botanical identity verification and ingredient testing. Testing capabilities include:
- Botanical identity authentication
- Total plate count, yeast, and mold testing
- Heavy metals analysis
- Pesticide screening
- USP compliance testing
Analytical instrumentation includes HPLC, UPLC-MS/MS, GC/MS, LC/MS, and ICP/MS, supported by independent third-party laboratory testing.
How the contract manufacturing process works
Six steps from first call to shipped lot, about 12 weeks end to end from approved formula and packaging. The order rarely changes; what moves the date is how much of the specification already exists when you arrive and how quickly packaging components can be secured.
1
Brief and feasibility
You tell us the product, the format, the actives you care about and the volume you expect. We tell you honestly whether it can be made as described, what would have to change, and whether custom or private label is the right route.
2
Formulation or formula review
Our formulators either develop the formula or take apart the one you brought. This is where actives levels, base, taste, solubility, preservation and regulatory framing are settled together rather than in sequence.
3
Bench samples and approval
You receive samples and we iterate until you sign off. Nothing scales until the sample is the product you actually want to sell.
4
Raw material qualification and pilot batch
Every incoming component is identity tested and qualified against the specification. A pilot batch proves the formula behaves the same at production scale as it did on the bench.
5
Production, fill and packaging
Full production runs under NSF GMP conditions with batch records at every stage. Packaging components are the usual pacing item inside that 12 weeks, which is why the schedule firms up once the pack is fixed.
6
Release testing, documentation and shipment
Finished lots are tested and released with the documentation package described below, then shipped from New York. Repeat runs start at step five unless the specification has changed.
What testing and documentation do you receive?
Every lot ships with a Certificate of Analysis. Behind it sits identity testing on incoming raw materials, in-process controls, finished product release testing and batch records retained under 21 CFR Part 111. You can request the underlying records, and you can audit the facility that produced them.
Per lot, with the shipment
- Certificate of Analysis for the finished lot
- Lot number and traceability back through the components used
- Finished product release results against the agreed specification
On request, for your own files
- Raw material identity test results and supplier qualification records
- Batch production records for the lot in question
- Facility certification documentation, including NSF GMP
- Stability data where a study has been run on your formula
Identity testing on incoming materials
Part 111 requires at least one appropriate test to verify the identity of every incoming dietary ingredient. That is a test we run, not a certificate we file. For botanicals in particular, identity is where substitution and adulteration are caught, and it is the reason a paper-only supplier chain is a liability.
Stability and shelf life
Shelf life is set by data, not by convention. Stability studies are run on your formula in your final packaging, because the pack is part of the result. We will tell you what study is appropriate for the format and what an interim shelf life can honestly be set at while it runs.
Who is responsible for what under 21 CFR Part 111
If your name is on the label, you are a manufacturer under 21 CFR Part 111 too. You cannot outsource that. Under §111.75 a firm that holds the label must independently qualify its supplier before relying on a Certificate of Analysis, confirm the COA with its own testing, document the qualification and periodically reconfirm it.
This surprises people. The common assumption is that hiring a GMP contract manufacturer transfers the compliance burden along with the production. It does not. A brand owner that distributes a dietary supplement holds its own obligations under Part 111, and FDA has issued warning letters to brand owners who relied on a manufacturer’s paperwork without doing their own qualification work. Read the rule at the eCFR, 21 CFR Part 111.
What that obligation looks like in practice
- You must qualify us as a supplier rather than simply accepting our COA at face value
- That qualification has to be documented, not merely done
- It has to be reconfirmed periodically, not established once at onboarding
- You need to be able to show the records if you are inspected
What BioB supplies to shorten that work
We treat your qualification file as part of the job rather than an interruption to it. That means: facility certification documentation you can drop straight into your supplier file; identity test results on incoming materials so you can see the verification actually happened; batch records on request for any lot you need to defend; a named quality contact who answers audit questions rather than routing them to sales; and an open door for on-site audits, because a supplier who will not be visited is telling you something.
None of this removes your obligation. It removes the part of it that is chasing a manufacturer for documents that should have been offered.
Why brands choose BioB Manufacturing
Grand View Research values the US dietary supplement contract manufacturing market at USD 6,649.3 million in 2025, growing to USD 16,644.3 million by 2033 at a 12.2% CAGR. Plenty of capacity exists. What is scarce is a manufacturer that makes its own actives, publishes its minimums and tells you what you are liable for.
We control the actives
Botanical extraction in house since 1972. No competitor ranking on this term controls its own extract supply, which means their traceability begins where a broker’s paperwork begins.
One US site
A single 160,000 square foot FDA-registered facility in New York. No import exposure, no tariff variable hidden in the landed cost, no offshore transit sitting between you and a stockout.
Published minimums
Our numbers are on this page. Compare that with the standard industry answer of “available upon request”, which exists to get you on a call before you can compare.
Liquids done properly
Including alcohol-free. Liquid supplements are the format most contract manufacturers quietly subcontract. Here they are the original business.
Ingestible and topical together
A brand launching a supplement and a companion topical gets one vendor, one quality system and one documentation package instead of two of everything.
We tell you what you own
The Part 111 responsibility split is on this page rather than buried in an onboarding pack. You should know your obligations before you sign, not after.
Contract manufacturing supplements: frequently asked questions
What is contract manufacturing for supplements?
Contract manufacturing for supplements is an arrangement in which a brand owns the product specification and a manufacturer produces it. The manufacturer sources or makes the raw materials, blends, fills, tests and documents every lot under 21 CFR Part 111. The brand owns the formula, the label and the regulatory responsibility attached to it.
How is contract manufacturing different from private label and white label?
Private label and white label both mean putting your brand on a formula the manufacturer already owns and sells to others. Contract manufacturing means the specification is yours: your ingredients, your levels, your release limits, and no competitor can order the same product. Private label is faster to launch; contract manufacturing is exclusive.
What are your minimum order quantities?
Liquid supplements under 8 oz start at 5,000 units. Liquid supplements 8 oz and larger start at 2,500 units. Capsules and tablets start at 300,000 units total across the run. Powders, oral care, pet wellness and other formats are confirmed at quote, because fill size and packaging drive the number.
What drives the cost per unit?
Five things, roughly in order: the actives and their potency, the format and fill size, the packaging components, your order volume against the minimum, and the testing scope. Botanical extracts vary widely in cost, and packaging is often the largest single line. We will not quote a per-unit figure before we know the formula and the pack.
Do I need a formula before I contact you?
No. Many projects arrive as a brief rather than a formula: a target audience, a format and the actives you want to lead with. Our formulators build from there. If you already have a specification, bring it and we will review it rather than start again.
Can you reformulate a product I already sell?
Yes. Reformulation is one of the three routes we run. Common reasons are an ingredient that has become hard to source, a base that needs to become alcohol-free, a taste problem, or a cost structure that no longer works. We rebuild around the constraint while holding what your customers recognize.
Can I transfer a formula I already own to you?
Yes. You keep ownership of the specification. We qualify the raw materials against it, run trial and pilot batches, and confirm that production output matches what you approved before full runs begin. Transfers usually surface documentation gaps in the original program, and we would rather find those before first production.
Do you provide a Certificate of Analysis for every lot?
Yes. Every lot ships with a Certificate of Analysis for the finished product. Behind it sit identity test results on incoming raw materials, in-process controls and batch production records, all retained under 21 CFR Part 111 and available on request for your own supplier qualification file.
Does using a GMP contract manufacturer make me compliant with 21 CFR Part 111?
No. A brand owner holding the label is itself a manufacturer under Part 111. Under §111.75 you must independently qualify your supplier rather than simply relying on a Certificate of Analysis: confirm it with your own testing, document the qualification, and periodically reconfirm it. We supply the records that shorten that work.
What identity testing do you run on incoming ingredients?
Part 111 requires at least one appropriate test to verify the identity of each incoming dietary ingredient before use. We run that testing rather than accepting a supplier certificate alone. For botanicals it is the control that catches substitution and adulteration, which is why a paper-only supply chain is a real liability.
Do you make the botanical extracts that go into our formula?
Yes. Our parent company, Bio-Botanica, extracts botanicals on the same Hauppauge campus: more than 20,000 kg per week using its Bio-Chelated® process, liquid compounding from 50 to 3,300 gallons, spray and vacuum tray drying for powders, and on-site quality control and microbiology.
Can I audit your facility?
Yes. The facility is in Hauppauge, New York, is FDA-registered and NSF GMP certified, and brand owners are welcome to audit it. We also supply certification documentation for your supplier file in advance. A contract manufacturer that will not host an audit is telling you something worth listening to.
How do you set shelf life, and do you run stability testing?
Shelf life is set from stability data on your formula in your final packaging, because the pack affects the result. We advise which study suits the format, run it, and tell you what interim shelf life can honestly be carried while the study completes. We do not assign a date by convention.
Tell us what you want to make
Send the brief, the formula or just the idea. You will get a straight answer on whether it can be made as described, which minimum applies, and whether custom or private label is genuinely the better route for you. No obligation, and we reply the same business day.
Get My QuotePrefer to talk it through first? Book a 30-minute call with Emily Slater